The effect of chiropractic care on infantile colic: results from a single-blind randomised controlled trial Lise Vilstrup Holm1,2, Dorte Ejg Jarbøl2 , Henrik Wulff Christensen1 , Jens Søndergaard2 and Lise Hestbæk1,3*

Abstract Background: Chiropractic care is commonly used to treat infantile colic. However large trials with parental blinding are missing.

Therefore, the purpose of this study is to evaluate the effect of chiropractic care on infantile colic.

Method: This is a multicenter, single-blind randomized controlled trial conducted in four Danish chiropractic clinics, 2015–2019. Information was distributed in the maternity wards and by maternal and child health nurses.

Children aged 2–14 weeks with unexplained excessive crying were recruited through home visits and randomized (1:1) to either chiropractic care or control group.

Both groups attended the chiropractic clinic twice a week for 2 weeks. The intervention group received chiropractic care, while the control group was not treated. The parents were not present in the treatment room and unaware of their child’s allocation.

The primary outcome was change in daily hours of crying before and after treatment. Secondary outcomes were changes in hours of sleep, hours being awake and content, gastrointestinal symptoms, colic status and satisfaction. All outcomes were based on parental diaries and a final questionnaire. Results: Of 200 recruited children, 185 completed the trial (treatment group n = 96; control group n = 89).

Duration of crying in the treatment group was reduced by 1.5 h compared with 1 h in the control group (mean difference − 0.6, 95% CI − 1.1 to − 0.1; P = 0.026), but when adjusted for baseline hours of crying, age and chiropractic clinic, the difference was not significant (P = 0.066).

The proportion obtaining a clinically important reduction of 1 h of crying was 63% in the treatment group and 47% in the control group (p = 0.037), and NNT was 6.5. We found no effect on any of the secondary outcomes.

Conclusion: Excessive crying was reduced by half an hour in favor of the group receiving chiropractic care compared with the control group, but not at a statistically significant level after adjustments. From a clinical perspective, the mean difference between the groups was small, but there were large individual differences, which emphasizes the need to investigate if subgroups of children, e.g. those with musculoskeletal problems, benefit more than others from chiropractic care.

Trial registration: Clinical Trials NCT02595515, registered 2 November 2015 Keywords: Infantile colic, Chiropractic, Randomized controlled trial, Manipulative treatment, Excessive crying

Holm et al. Chiropractic & Manual Therapies (2021) 29:15 https://doi.org/10.1186/s12998-021-00371-8

https://chiropracticaustralia.org.au/wp-content/uploads/2021/08/Best-Article-of-the-Quarter-Q2-SUMMARY.pdf

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What Does Your Central Nervous System Do?

Your central nervous system, or your CNS consists of two parts: the brain and the spinal cord. The brain is the center of our thoughts, the interpreter of our external environment, and the origin of control over body movement.

A healthy spine, coupled with a healthy nervous system, is crucial in terms of maintaining whole body health. Any alteration of spinal structure or function may cause irritation of the central nervous system or the outer spinal nerves that are protected as they travel to organs or muscles. This alteration is known to chiropractors as “pinched nerve”. Protection of the central nervous system allows it to function optimally via the spinal cord, housed within the spine, which controls the function of every single cell, tissue and organ in the body.